49ers Pro Bowl Stars Trent Williams and Ricky Pearsall Out vs. Seahawks

UPDATE: The San Francisco 49ers are facing a major setback as Pro Bowl left tackle Trent Williams and receiver Ricky Pearsall are both sidelined due to injuries for their crucial Week 18 clash against the Seattle Seahawks. This game, pivotal for the division title, is unfolding tonight, December 28, 2025.

Williams sustained his injury on the very first play during last week’s victory over the Chicago Bears, leaving him unable to participate after being listed as questionable. Pearsall, on the other hand, continues to struggle with a knee issue and will miss his eighth game this season, despite limited practice throughout the week.

In Williams’ absence, rookie Austen Pleasants is making his first career start, with Brandon Parker elevated from the practice squad to serve as a reserve. This puts significant pressure on the 49ers’ offensive line as they prepare to face a fierce Seahawks defense.

Pearsall has recorded 36 catches for 528 yards this season, making his absence felt in the lineup. With Pearsall out, Kendrick Bourne and Demarcus Robinson are set to step up and fill the gap in the receiving corps.

In a slight boost for the 49ers, Pro Bowl tight end George Kittle returns to the lineup after missing last week’s game due to an ankle injury. Meanwhile, cornerback Upton Stout (concussion) and defensive end Keion White (groin) are also active after being previously listed as questionable.

For the Seahawks, backup left tackle Josh Jones is active despite ankle and knee injuries, stepping in for the sidelined Charles Cross. The Seahawks also elevated running back Cam Akers and cornerback Tyler Hall from the practice squad for this crucial matchup.

As fans eagerly await kickoff, the 49ers must regroup and adapt to these unexpected absences. The stakes are incredibly high tonight, and all eyes will be on how San Francisco navigates this challenge against the Seahawks. This developing situation continues to unfold, and updates are expected as the game progresses. Stay tuned for the latest developments!